Resistance training modulates TNF-α and improves muscle strength in people living with HIV taking Highly Active Antiretroviral Therapy
DOI:
https://doi.org/10.12820/rbafs.26e0227Keywords:
HIV/AIDS, Resistance training, Public healthAbstract
The study aims to evaluate the contribution of resistance training in oxidative stress and strength markers of people living with HIV. This is a non randomized clinical trial, with a discontinuous time series design, and sampling by volunteers belonging to the Municipal Care Program for STD/HIV/AIDS (PAMDHA) with High Activity Antiretroviral Therapy treatment. Body composition, physical fitness, oxidative damage and antioxidant enzymes were evaluated. In the anthropometric variables among men, differences were found between the groups in the values of waist circumference (pre = 93.95 ± 8.21; post = 92.25 ± 7.46) and fat percentage (pre = 88.5 ± 6.35; post = 18.57 ± 7.74). Strength levels indicated improvement in both groups (p < 0.05). The analysis of carbonyl groups, the activity of the antioxidant enzyme Catalase, Superoxide Dismutase (SOD), Thiobarbituric acid reactive substances (TBARS) and the levels of TNF-α in serum preferentially HIV+, did not differ significantly (p < 0.05). The results showed that moderate-intensity resistance training can be used as an adjunct therapeutic agent to the use of ART for the maintenance and improvement of the health of people with HIV.
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